The Bop It! Spider-Man Edition features gameplay inspired by Marvel's Spider-Man, complete with voiceovers from the character. Players must quickly respond to commands—Bop It, Twist It, or Pull It—in random sequences to test reflexes. A web-slinging action is triggered by pressing the top of Spider-Man's head. The game supports both solo play and group competition with its Solo and Pass-It modes, making it suitable for individual or multiplayer fun.