Twisted Luck challenges players to infiltrate a Monte Carlo casino and disrupt its operations by stealing a powerful relic at its core. This relic, known as the Wellspring of Fortune, grants the casino unnatural control over luck itself. The scenario functions as a standalone adventure or can be integrated into an existing campaign for expanded gameplay. When used as a side-story within The Scarlet Keys campaign, it includes additional features to complement the larger narrative. To play, only the Arkham Horror: The Card Game Revised Core Set is required.